When importing a large dataset into GSS, I got a GSS error "The parameter is incorrect" when I tried to run Data/Calculate. After some searching, I figured out that I had imported a few cells whose low analyte concentrations (e.g., 0.0001 mg/L) got truncated (e.g, to 0.000 mg/L). After rectifiyng these, Calculate works fine. So be careful when importing that you keep all the data.